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Pneumococcal antigens
SSI Diagnostica Group’s expert knowledge in purifying antigens has been used in the manufacture of reagents for in vitro diagnostics and research. SSI Diagnostica Group can supply a broad range of pneumococcal antigens including cell wall polysaccharides (CWPS), purified from a non-capsule pneumococcus and serotype‑specific capsular polysaccharides.
Pneumococcal antigens product overview
| Item | Primary use | Key composition | Additional info |
|---|---|---|---|
| CWPS | Adsorption material in immunological investigations (e.g. ELISA) both in surveillance and vaccine industry, to evaluate whether any vaccination/ revaccination is desirable. | Pneumococcal CWPS1 [1,2] | Standard CWPS adsorption |
| CWPS Multi | Adsorption material in immunological investigations (e.g. ELISA) both in surveillance and vaccine industry, to evaluate whether any vaccination/ revaccination is desirable. | Pneumococcal CWPS1 (50%) + CWPS2 (50%) [1,2] | Adsorption with the 22F capsule, as recommended by WHO for ELISA [3], is not required [1]. |
| Pneumococcal capsules | Antigen for immunological investigations, ELISA antibody assays (RUO). | Serotype-specific pneumococcal capsular polysaccharides purified from reference strains. | Full serotype catalog (types 1–48) for assay design and evaluation |
- Skovsted IC, Kerrn MB, Sonne-Hansen J, Sauer LE, Nielsen AK, Konradsen HB, Petersen BO, Nyberg NT, Duus JO. Purification and structure characterization of the active component in the pneumococcal 22F polysaccharide capsule used for adsorption in pneumococcal enzyme-linked immunosorbent assays. Vaccine. 2007 Aug 29;25(35):6490-500.
- Pneumococcal Capsules and Their Types: Past, Present, and Future. Geno KA, Gilbert GL, Song JY, Skovsted IC, Klugman KP, Jones C, Konradsen HB, Nahm MH. Clin Microbiol Rev. 2015 Jul;28(3):871-99. doi: 10.1128/CMR.00024-15. Review. PMID: 26085553
- Training manual for Enzyme linked immunosorbent assay for the quantitation of Streptococcus pneumoniae serotype specific IgG (Pn PS ELISA).
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